Head injury as a trigger of Parry-Romberg syndrome: A case report and review of etiology

Introduction: this is a case of a patient with the rare entity of Parry-romberg syndrome (Prs) which discuss the etiological association with preceding head trauma as well as the possible therapeutic role of vitamin b12, with a brief review of literature. case report: A 22-year-old female presented with a history of head injury preceding the progressive onset of right-sided facial pain and atrophy, evident facial asymmetry with periorbital hyperpigmentation on the right side of the face, enophthalmos and watering of the right eye. Laboratory investigations revealed a low vitamin b12 level. A final diagnosis of Parryromberg syndrome (“progressive hemifacial atrophy”) was based on clinical and a radiological examination. conclusion: Parry-romberg syndrome is an incompletely understood selflimiting degenerative condition, characterized by unilateral atrophic changes of the face. the pathophysiology of the syndrome remains unclear, but the etiologic relevance of factors like head injury and vitamin b12 deficiency needs to be investigated in further collective studies.